Functional dyspepsia (FD) refers to a group of common dyspepsia syndromes caused by non-organic lesions. In addition to the mechanisms involved in gastric acid secretion, Hp infection and psychological factors, gastrointestinal dysfunction also plays an important role.
Traditional Chinese medicine has obvious advantages in the treatment of functional diseases, and has the characteristics of reliable curative effect, small side effects, and short treatment course.
Clinical literature mostly classifies FD as “fullness, stomach pain, noisy, appetite, vomiting” and other categories.
Etiology and pathogenesis The author summarized the pathogenic factors of 60 patients with FD in two groups, and found that the incidence of FD was more closely related to emotional factors and dietary insufficiency.
Of the two groups of cases, 46 were due to emotional factors, accounting for 76.
Thirty-seven cases were affected by dietary insufficiency, accounting for 61.
The liver belongs to the wood, the main dredge and depression, the emotions; the spleen is transported, the stomach is accepted, the territory.
In relation to wood and soil, the transport of the spleen and stomach depends on the drainage of the liver.
Emotional depression, liver loss and drainage will inevitably make the spleen and stomach dysfunctional, and lose the ability to absorb the disease, which is also called “muyu ride soil”.
“Su Wen · Liu Yuan Zheng Ji Da Lun” said: “Mu Yu’s disease, the people’s disease, stomach pain, beware of pain.
“The Clinical Guideline Case Report also pointed out:” The liver is the source of the onset, and the stomach is the place where the disease is transmitted. ”
“Shen Jin’ao said,” Stomach pain is also caused by dry stomach.
However, the liver gas phase multiplication is even more serious, with wooden violence, and Zhengke also.
“Blood Syndrome” said: “The nature of wood is drunk, and gas is eaten into the stomach.
It is inevitable that the liver cannot drain the water valley, and the evidence of fullness in the drain is inevitable.
Insufficient diet, internal trauma and stagnation of the stomach cause blockage of the air machine, stomach loss and fall, earth stagnation and wood stagnation, leading to liver and stomach qi stagnation, the first disease in the stomach, chronic illness and injury to the spleen, leading to liver depression and spleen deficiency, liverStomach stagnation, liver, spleen and stomach disharmony, various diseases are clustered.
“Su Wen · Tai Yin Yang Ming Lun” states: “Eaters who are not eating properly, who live from time to time, yin, . when they enter the five internal organs are full of occlusion.
“The Treatise on Febrile Diseases · Distinguishing the Sun’s Diseases and Treating the Symptoms of the Sun” pointed out: “There is discord in the stomach, the heart is hard, and the odor is dry.
“The Secret of the Blue Room · Zhongman Bloating” said: “People who eat cold or cold and have a weak spleen and stomach will be full.
“Traditional Chinese Medicine Treatment” is aimed at the pathogenesis of FD liver depression and spleen deficiency, liver and stomach qi stagnation.
We selected 60 patients with FD and randomly divided them into the treatment group of Shugan Jianpi and Weifang (Chaihu, Stir-fried Bai Zhi, Angelica, Stir-fried Atractylodes, Poria, Sunburn, Coriander Shell, Stir-Fried Chenpi, Yujin, Shenqu, etc.) in the treatment group 30There were 30 cases and domperidone control group.
After 4 weeks of treatment, the total clinical effective rate of FD in the treatment group was 93.
3%, compared with 70% in the control group, there was a significant difference between the two groups (P <0. 05). And the treatment group was better than the control group in improving the symptoms of chest tightness or hi-fat, poor appetite, noisy or acid in the stomach, fatigue, and thin stools, which had statistical significance. The meaning of Shugan Jianpi and Wei Fangzong Xiaoyao San is to use Bupleurum to relieve stagnation and relieve depression; to use Angelica and Baizhi to nourish the liver and soften the liver and to improve its body;Zhipi replenishes the soil and strengthens the spleen, cultivates its essence and strengthens its fortune; Chenpi, crustacean harmonizes qi and stomach, and follows its harmony; Yujin Xingqihuoxue helps Chaihu Sanganyu, and because of the long course of the disease and stasis,And Qi Qi stagnation also caused poor blood flow, so turmeric was added to Qi and blood circulation to eliminate blood stasis; Shenqu digestion and stomach. Shugan Jianpi and Weifang recipes treat liver, spleen and stomach in the same way, coexistence of qi and blood, and perform the functions of spleen and spleen, stomach-tongue, qi and blood. Modern pharmacological research shows that Atractylodes macrocephala and Poria cocos can both promote gastrointestinal peristalsis and inhibit hypertrophic large intestinal motor function, and have dual regulating effects on the overall gastrointestinal motor function. Bupleurum and clam shell have obvious functions of enhancing gastric fluid emptying and small intestine propulsion. Atractylodes, Shenqu, Chenpi can promote the secretion of gastrointestinal digestive juice and accelerate gastrointestinal motility. Chenpi not only increases gastrointestinal motility, but also makes it rhythmic. Paeonia lactiflora contains paeoniflorin, which has the effect of relieving abdominal cramps and relieves pain, has synergistic effects with licorice, and has antiulcer and antibacterial effects. Licorice has the effect of adsorbing gastric acid, reducing pepsin activity and protecting gastric mucosa. Turmeric has the effect of stimulating gastric acid secretion, and also stimulates secretin secretion, which increases the HCO3-concentration in duodenal fluid, so it has the effect of maintaining the pH of the gastrointestinal tract and is beneficial to the digestion and absorption of food. Turmeric also has a regulating effect on immune function, can resist inflammation, allergy, and free radical damage, so it also has a certain effect on improving the defense function of the gastrointestinal mucosa.